Thursday, October 14, 2010

Mitochondria, may explain the inflammation after trauma

Biomedical Beat - A monthly digest of research news from NIGMS

IN THIS ISSUE ...
21 April 2010

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Courtesy of Zachery R. Smith, a graduate student in the Jeff Long lab at the Salk Institute for Biological Studies.

The earliest of the Arabidopsis plant embryo selects pages: even if the other end of the shoot, constitute the entire agreement between you and the other to take root underground. short of RNA in bottom half (blue) make sure that the genes which make up the shoot is expressed only in the embryo's top half of the (green), eventually allowing the seedling with dignity, and to be completely eliminated. as the animal plant follow carefully organised polarization plan and errors can cause a significant developmental defects, as stated above and below ground. shoots Because complex gene networks, coordinate the development of plants and animals share important similarities, study the model of the organism from Arabidopsis polarity — — could also help us to better understand human development. Zachery r. Smith, Jeff Long-Salk Institute for Biological Studies graduate student of the courtesy.

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Long lab
Abstract (natural, commencing March 18)

Mice lacking the p21 gene can regenerate damaged tissue without scarring. Courtesy of James Hayden, Microscopy Core Facility.

Creatures such as lizards, salamanders, flatworms and create a Starfish again the parts of the body. Now scientists have identified a gene that could allow regeneration in mammals. Wistar Institute Ellen Heber-Katz immunologist, led by the Working Group noted that incomplete p21 mice — gene, cell cycle regulated — can replace the lost or damaged tissue scarring.Researchers found previously, that position can heal completely mice pierced ears current research indicates that the p21 was passive these rodents ear cells.The most recent findings suggest that researchers may be able to increase, as one human healing process.

This work was supported by the NIH's National Cancer Institute.

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Heber Katz profile
Abstract (March 30, commencing on the PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES)

Mitochondria, which contain their own genetic material and protein-making machinery, may trigger inflammation after injury. Courtesy of Nicolle Rager, National Science Foundation.

A serious physical injury to elicit the same overblown than bacteria Sepsis, monitoring, long puzzled scientists is inflammatory response. Researchers led by trauma surgeon Beth Israel Deaconess Medical Center I think now, Carl Hauser works with a explanation After injury., mitochondria, — the cellular organelles is believed to have originated from the bacteria — can oil spill recovery into bloodstream.The results of the mitochondria, the researchers will look enough like bacteria invaders to restart the resistance reaction.They also show that the use of antibiotics in food-producing animals to deal with this trauma based on inflammation may be useless, and that to find the means to combat such immunity shall directly can be more efficient.

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Profile of Hauser
Abstract (natural, commencing March 4)

In this fruit fly embryo, a protein (red) important for the development of the head is concentrated at one end, where it monopolizes MAPK. Courtesy of the Shvartsman lab.

The nature of the formatted resources, such as the food and the minimum age for drivers ' mates competition. our bodies are different — molecular competition affects every part of our physiology, our blood pressure how our dinner may be digested. Stanislav Shvartsman, systems biologist at the University of Princeton, led researchers found new biochemical competition, which affects the function of the amount known as the MAPK. Multiple molecules are competing in the binding order MAPK, which is an important element in the development of all plants and animals. competition is a high stakes — the winners of our bodies, affecting not only the development, but also how the risk of the spread of cancer.

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Shvartsman lab
Abstract (current Biology, commencing March 9)

Researchers use census data to create a synthetic population for simulating disease spread.

Fun fact: your calculation results can help computer scientists model the spread of communicable diseases in the United States the. as part of the NIGMS ' models of Infectious Disease Agent Study research geographer Bill Wheaton, RTI International established a complete synthetic population is the same as the analysis of every city, County and State 2000 census data. [1] [2] he and his update with data from the population census 2010. Researchers integrate better Simulate outbreaks and the best ways to address computer models, in addition to the population of the population. on the other hand, allows modelers and actual outbreaks of a timetable consistent with the political decision-makers.

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MIDAS

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